Apparently, even Jane Austen would have a hard time getting a novel published today:
David Lassman sent off to 18 publishers assorted chapters from Austen novels in which he changed just the titles and the names of the characters.
Seventeen publishers rejected or ignored his bid for literary glory. Only one spotted the ruse and told him not to mimic Pride and Prejudice so closely.
— Reuters
However, I do find it disconcerting that seventeen of the eighteen publishers didn't recognize (or at least acknowledge) Austen's work.
